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KMID : 1007320150210020089
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Journal of the Korean Society of Menopause
2015 Volume.21 No. 2 p.89 ~ p.92
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Expression of Vitamin D Receptor in Seminal Vesicles of Cholesterol Formula Mice
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Kim Tae-Hee
Lee Hae-Hyeog
Kim Jun-Mo
Choi Seung-Do
Lee A-Rum
Hwang Sun-Yong
Kim Mi-Jin
Kim Yeon-Suk
Yeom Seung-Rae
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Abstract
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Objectives: Genomic function of vitamin D receptor (VDR) indicates spermatogenesis that is important for in male reproductive organ authors evaluated the VDR expression in seminal vesicles with high cholesterol (HC) formula diet rat, because there is no report about relationship or difference in VDR in seminal vesicles between HC and control.
Methods: Male C57BL/6 mice aged 5 weeks were raised for 13 weeks. After one week of adaptation-period, they were fed
different diet on normal AIN-93G diet, or HC diet containing 2% cholesterol for 12 weeks. The antibodies used were rabbit anti-VDR primary polyclonal.
Results: There was no significant difference in VDR reactivity in seminal vesicles, body weight of rat and weight of seminal vesicles between HC group and normal control group.
Conclusion: Our data give the no difference in expression of VDR of seminal vesicles rat between HC formula diet and normal AIN-93G diet. But we confirmed the VDR expression in seminal vesicles.
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KEYWORD
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Cholesterol, Seminal vesicles, Vitamin D receptor
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